Description

Cy3 Dic18 CAS NO 22366-93-4 is a specialized cyanine dye derivative, specifically a dicarbocyanine dye with an octadecyl (C18) chain, designed for advanced labeling and detection applications. Its core value lies in its strong fluorescence in the near-infrared region, offering deep tissue penetration and minimal background interference for sensitive bioimaging. This product is essential for researchers and manufacturers in the life sciences, diagnostics, and pharmaceutical development sectors who require high-performance, lipophilic fluorescent probes for membrane studies, cell tracking, and in vivo imaging.

Application

• Lipid Membrane and Vesicle Labeling: Ideal for incorporating into liposomes, lipid nanoparticles (LNPs), and cell membranes due to its hydrophobic C18 tail for studying dynamics and fusion.
• In Vivo and Deep-Tissue Fluorescence Imaging: Used as a contrast agent in preclinical research for non-invasive tracking of labeled cells, tumors, or drug delivery carriers.
• Flow Cytometry and Cell Sorting: Employed for staining and tracking specific cell populations based on membrane incorporation.
• Bioconjugation and Probe Development: Serves as a key fluorescent component for synthesizing custom-labeled antibodies, peptides, or other biomolecules.
• Material Science and Sensor Development: Incorporated into polymeric matrices or nanomaterials to create fluorescent sensors and functional materials.
• Diagnostic Assay Development: Utilized in the design of lateral flow assays, ELISA, and other diagnostic platforms requiring stable, bright near-infrared signals.

Basic Information

Product Name	Cy3 Dic18
CAS No.	22366-93-4
Molecular Formula	C55H81IN2O3S2
Molecular Weight	1001.27 g/mol
Synonyms	1,1'-Dioctadecyl-3,3,3',3'-Tetramethylindocarbocyanine Perchlorate; DiIC18(3); DiI; 3,3'-Dioctadecylindocarbocyanine Perchlorate; DiIC18(3) (Perchlorate); DiI (C18) Perchlorate; DiIC18(3) Lipophilic Tracer; 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate
EINECS	Contact for details

Quality Control

Our Cy3 Dic18 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high performance. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectrophotometry for absorbance/fluorescence verification, and identity confirmation (IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in research and development towards regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature before opening to minimize condensation and moisture uptake. For long-term stability, store under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Dark red to purple solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption Maximum (λmax)	548 - 552 nm (in methanol)
Emission Maximum	565 - 570 nm (in methanol)
Extinction Coefficient (ε)	≥ 1.4 x 105 L·mol-1·cm-1
Solubility	Soluble in DMF, DMSO, ethanol, chloroform; insoluble in water
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.