Description

1,3,5-Tri-o-Benzoyl-D-Ribofuranose is a key protected ribose derivative, essential as a sophisticated chiral building block in organic synthesis. Its primary value lies in providing a selectively benzoylated ribofuranose scaffold, crucial for constructing nucleoside analogs and other complex bioactive molecules. This high-purity intermediate is critically needed by pharmaceutical R&D teams and fine chemical manufacturers specializing in antiviral, anticancer, and nucleotide-based therapeutics.

Application

• Nucleoside & Nucleotide Synthesis: A vital protected intermediate for the production of modified nucleosides used in antiviral and anticancer drug candidates.
• Pharmaceutical Intermediates: Serves as a chiral precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs).
• Antiviral Pro-drug Development: Used in the research and manufacture of pro-drugs for hepatitis B (HBV) and hepatitis C (HCV) treatments.
• Oligonucleotide Chemistry: Employed in the synthesis of oligonucleotide fragments for research and therapeutic applications.
• Carbohydrate Chemistry Research: A valuable reagent for academic and industrial research into glycosylation reactions and sugar chemistry.
• Fine Chemical Production: Acts as a building block for various specialty chemicals requiring a defined ribose configuration.

Basic Information

Product Name	1,3,5-Tri-o-Benzoyl-D-Ribofuranose
CAS No.	22224-41-5
Molecular Formula	C26H22O8
Molecular Weight	462.45 g/mol
Synonyms	1,3,5-Tri-O-benzoyl-α-D-ribofuranose; D-Ribofuranose, 1,3,5-tribenzoate; 1,3,5-Tri-O-benzoyl-D-ribofuranose; Tribenzoyl-D-ribofuranose; α-D-Ribofuranose 1,3,5-tribenzoate; 2,3,5-Tri-O-benzoyl-D-ribofuranose (common misnomer); NSC 404058; 1,3,5-Tri-O-benzoyl-α/β-D-ribofuranose mixture
EINECS	Contact for details

Quality Control

Our 1,3,5-Tri-o-Benzoyl-D-Ribofuranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and loss on drying. We provide Certificates of Analysis (COA) with full traceability to ensure compliance with your research and cGMP-grade manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.