Description

2-(Chloromethyl)-1,4-Dioxaspiro[4.4]Nonane is a versatile spirocyclic acetal building block with a reactive chloromethyl handle. This compound matters for its role as a key synthetic intermediate in the production of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced material sectors for constructing molecular scaffolds and introducing functional groups.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for spirocyclic and heterocyclic compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require complex, functionalized cyclic structures.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Organic Synthesis: Employed as a protected form of a carbonyl compound (e.g., a ketone) with a pendant electrophilic site for further functionalization via nucleophilic substitution.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral or multidentate ligands for asymmetric catalysis and metal complexation.
• Chemical Biology Probes: Functions as a starting material for synthesizing molecular probes and tags used in biochemical and cellular studies.

Basic Information

Product Name	2-(Chloromethyl)-1,4-Dioxaspiro[4.4]Nonane
CAS No.	22195-53-5
Molecular Formula	C8H13ClO2
Molecular Weight	176.64 g/mol
Synonyms	2-(Chloromethyl)-1,4-dioxaspiro[4.4]nonane; 1,4-Dioxaspiro[4.4]nonane, 2-(chloromethyl)-; 2-Chloromethyl-1,4-dioxaspiro[4.4]nonane; 2-(Chloromethyl)-1,4-dioxaspiro[4,4]nonane; 2-(Chloromethyl)-1,4-dioxaspiro(4,4)nonane; 2-Chloromethyl-1,4-dioxaspiro(4,4)nonane; 2-(Chloromethyl)-1,4-dioxaspiro[4.4]nonane (CAS 22195-53-5); Spirocyclic Chloromethyl Acetal
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-1,4-Dioxaspiro[4.4]Nonane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.