Description

1-O,2-O:3-O,5-o-Dibenzylidene-α-D-Glucofuranose Benzoate is a key protected carbohydrate intermediate, specifically a fully benzylidene-protected glucofuranose derivative with a benzoate ester at the anomeric position. This compound is critical for synthetic chemists as it provides a versatile, multi-protected scaffold for the selective manipulation of sugar hydroxyl groups in complex oligosaccharide and nucleoside synthesis. It is primarily required by research institutions and pharmaceutical development companies engaged in advanced carbohydrate chemistry, glycobiology research, and the production of novel therapeutic agents.

Application

• Advanced Glycosylation Reactions: Serves as a pivotal building block for the stereoselective synthesis of complex oligosaccharides and glycoconjugates.
• Nucleoside & Nucleotide Analog Synthesis: Used as a protected sugar moiety in the preparation of modified nucleosides for antiviral and anticancer drug candidates.
• Glycobiology Research: Employed in the study of carbohydrate-protein interactions and enzymatic processes by providing a defined, protected substrate.
• Pharmaceutical Intermediate: Acts as a high-value precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting infectious diseases and metabolic disorders.
• Chemical Biology Probe Development: Utilized to create labeled or tagged carbohydrate probes for diagnostic and mechanistic studies.
• Chiral Auxiliary and Ligand Synthesis: Its rigid, chiral structure can be leveraged to develop asymmetric catalysts or resolving agents.

Basic Information

Product Name	1-O,2-O:3-O,5-o-Dibenzylidene-α-D-Glucofuranose Benzoate
CAS No.	22154-73-0
Molecular Formula	C27H24O7
Molecular Weight	460.47 g/mol
Synonyms	α-D-Glucofuranose, 1,2:3,5-bis-O-(phenylmethylene)-, 1-benzoate; 1,2:3,5-Di-O-benzylidene-α-D-glucofuranose 1-benzoate; 1-O-Benzoyl-2,3:5,6-di-O-benzylidene-α-D-glucofuranose; Di-O-benzylidene-D-glucofuranose benzoate; 1,2:3,5-Dibenzylidene-α-D-glucofuranose 1-benzoate; Protected Glucofuranose Benzoate; D-Glucofuranose, 1,2:3,5-bis-O-(phenylmethylene)-, 1-benzoate, α-
EINECS	Contact for details

Quality Control

Our 1-O,2-O:3-O,5-o-Dibenzylidene-α-D-Glucofuranose Benzoate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical intermediates, and custom synthesis to meet specific purity requirements (e.g., >98%, >99%) is available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled under inert atmosphere for long-term storage to maintain stability. Keep the container tightly sealed in a desiccator to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Specification available upon request
Specific Rotation	Specification available upon request
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.