Description

[(E)-3-Methyl-3-Penten-1-Ynyl]Phosphonic Acid Diethyl Ester is a specialized organophosphorus compound featuring a conjugated enyne system, making it a valuable building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique structure enables precise molecular construction. It is needed by research and development chemists, process development scientists, and manufacturers in the fine chemical, pharmaceutical, and crop protection industries.

Application

• Pharmaceutical Intermediate: Serves as a critical synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring complex alkynylphosphonate motifs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the phosphonate group can act as a bioisostere or functional handle.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Ligand and Catalyst Development: Employed in the creation of novel phosphonate-based ligands for metal-catalyzed reactions, including cross-coupling and polymerization processes.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme mechanisms.
• Organic Synthesis Building Block: A versatile reagent for Horner-Wadsworth-Emmons (HWE) olefination and other carbon-carbon bond-forming reactions to construct complex organic molecules.

Basic Information

Product Name	[(E)-3-Methyl-3-Penten-1-Ynyl]Phosphonic Acid Diethyl Ester
CAS No.	22152-31-4
Molecular Formula	C10H17O3P
Molecular Weight	216.21 g/mol
Synonyms	Diethyl (E)-3-Methyl-3-penten-1-yn-1-ylphosphonate; Diethyl (3-Methylpent-3-en-1-yn-1-yl)phosphonate; (E)-Diethyl (3-Methyl-3-penten-1-ynyl)phosphonate; 3-Methyl-3-penten-1-ynylphosphonic Acid Diethyl Ester; Phosphonic Acid, [(3-Methyl-3-penten-1-ynyl)]-, Diethyl Ester, (E)-; Diethyl (1E)-3-Methyl-3-penten-1-yn-1-ylphosphonate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards and customer specifications. Each batch is characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, providing full transparency on all critical quality attributes. We adhere to a quality management system to ensure reliable supply and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Typical: 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.