Description

(-)-2-o-Benzoyl-L-Malic Acid is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its specific stereochemistry and functional groups, which make it a critical precursor for the development of enantiomerically pure pharmaceuticals and fine chemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for asymmetric synthesis and complex molecule construction.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting specific enantiomeric activity.
• Asymmetric Synthesis: Serves as a building block for constructing complex molecules with defined stereocenters in medicinal chemistry and process development.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, fragrances, and advanced materials requiring high optical purity.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme mechanisms, chiral recognition, and developing new synthetic methodologies.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides, fungicides, and plant growth regulators where chirality affects biological activity.
• Catalyst and Ligand Preparation: Useful for synthesizing chiral ligands and organocatalysts used in stereoselective transformations.

Basic Information

Product Name	(-)-2-o-Benzoyl-L-Malic Acid
CAS No.	22138-51-8
Molecular Formula	C11H10O6
Molecular Weight	238.19 g/mol
Synonyms	L-(-)-2-Benzoyloxy-3-carboxypropanoic Acid; (2S)-2-(Benzoyloxy)butanedioic Acid; (-)-2-Benzoyloxy-L-malic Acid; O-Benzoyl-L-malic Acid; (S)-2-(Benzoyloxy)succinic Acid; L-Malic Acid 2-O-benzoate; 2-O-Benzoyl-L-malic Acid
EINECS	244-787-6

Quality Control

Our (-)-2-o-Benzoyl-L-Malic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We employ advanced analytical techniques, including HPLC, chiral analysis, and NMR, to verify identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.