Description

Chloromethyl Chloroformate is a highly reactive bifunctional reagent primarily used as a key intermediate in organic synthesis. Its value lies in its ability to introduce both chloromethyl and chloroformyl groups, facilitating the production of more complex molecules. This compound is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for carbamate and carbonate prodrugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where it acts as a versatile linker and protecting group.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the manufacture of specialty polymers and resins with specific functional properties.
• Chemical Research & Development: Employed in laboratory-scale reactions to create novel compounds, including dyes, pigments, and liquid crystals.
• Peptide Modification: Utilized for the selective protection of amino groups during complex peptide synthesis.

Basic Information

Product Name	Chloromethyl Chloroformate
CAS No.	22128-62-7
Molecular Formula	C2H2Cl2O2
Molecular Weight	128.94 g/mol
Synonyms	Chloromethyl carbonochloridate; Chloro(chloromethoxy)methanone; Chloroformic acid chloromethyl ester; (Chloromethoxy)carbonyl chloride; Chloromethyl chloroformate; CClF; Methyl chlorocarbonate chloride; Carbonochloridic acid, chloromethyl ester (IUPAC)
EINECS	244-774-7

Quality Control

Our Chloromethyl Chloroformate is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including gas chromatography (GC) and titration methods, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) confirming identity, assay, and impurity profiles is provided with each shipment to guarantee it meets your specific application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile and hygroscopic nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Density (at 20°C)	1.45 - 1.50 g/mL
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.