Description

Trofosfamide CAS NO 22089-22-1 is an alkylating agent belonging to the oxazaphosphorine class of nitrogen mustards. This compound is a critical intermediate in pharmaceutical research and development, particularly for the synthesis of chemotherapeutic agents. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries focused on oncology drug discovery and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for chemotherapeutic drugs.
• Oncology Research: Used in biochemical and pharmacological research to study alkylating agents and their mechanisms of action against cancer cells.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Preclinical Development: Employed in the development and testing of novel nitrogen mustard derivatives for potential therapeutic use.
• Chemical Synthesis: Utilized in organic synthesis for the preparation of complex molecules containing the oxazaphosphorine core structure.

Basic Information

Product Name	Trofosfamide
CAS No.	22089-22-1
Molecular Formula	C₉H₁₈Cl₃N₂O₂P
Molecular Weight	323.58 g/mol
Synonyms	N,N-Bis(2-chloroethyl)-N',N''-diethylphosphoric triamide; Ixoten; A-4828; A 4828; Trofosfamid; NSC-109723; 2-[Bis(2-chloroethyl)amino]-N,N-diethyl-1,3,2-oxazaphosphinan-2-amine 2-oxide
EINECS	244-782-7

Quality Control

Our Trofosfamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other chromatographic techniques, to ensure it meets stringent specifications for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.