Description

n-Methyl Cyclophosphamide is a synthetic alkylating agent and a derivative of the nitrogen mustard class of chemotherapeutic compounds. This intermediate is of significant value in pharmaceutical research and development, particularly for the synthesis of more complex therapeutic agents and prodrugs. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in oncology drug discovery and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel chemotherapeutic agents and prodrugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate alkylating mechanisms and cytotoxic effects.
• Chemical Synthesis: Serves as a precursor for the development of other cyclophosphamide analogs and nitrogen mustard derivatives.
• Bioconjugation Studies: Employed in the development of antibody-drug conjugates (ADCs) and targeted drug delivery systems.
• Metabolism Studies: Utilized as a reference standard or metabolite in pharmacokinetic and drug metabolism research.

Basic Information

Product Name	n-Methyl Cyclophosphamide
CAS No.	22089-17-4
Molecular Formula	C7H15Cl2N2O2P
Molecular Weight	261.09 g/mol
Synonyms	N-Methylcyclophosphamide; 2-[Bis(2-chloroethyl)amino]-N-methyltetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide; Methylcyclophosphamide; NSC 51325; Cyclophosphamide Monomethyl Derivative; N-Methyl Cyclophosphamide Monohydrate (common form)
EINECS	Contact for details

Quality Control

Our n-Methyl Cyclophosphamide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.