Description

Pentafluoroethyl Ethyl Ether is a highly fluorinated ether compound, identified by CAS NO 22052-81-9. It serves as a valuable intermediate and specialty solvent in advanced chemical synthesis, prized for its unique combination of high volatility and chemical inertness. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty materials sectors seeking to introduce fluorine for enhanced product performance.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) where the pentafluoroethyl group is required for metabolic stability or bioavailability.
• Agrochemical Synthesis: Acts as a key building block for creating novel herbicides and pesticides with improved efficacy and environmental profiles.
• Specialty Solvent: Employed in demanding chemical reactions and purification processes where high volatility and non-reactivity are critical.
• Fluorinated Material Production: Serves as a precursor in the manufacture of specialty polymers, surfactants, and coatings that require oil, water, and stain resistance.
• Electronics Industry: Potential use in the formulation of specialty cleaning agents or etching gases for semiconductor manufacturing.
• Research & Development: A valuable reagent for academic and industrial research exploring new fluorination methodologies and fluorine chemistry.

Basic Information

Product Name	Pentafluoroethyl Ethyl Ether
CAS No.	22052-81-9
Molecular Formula	C4H5F5O
Molecular Weight	164.08 g/mol
Synonyms	Ethyl Pentafluoroethyl Ether; 1,1,2,2,2-Pentafluoroethyl Ethyl Ether; Ethoxyperfluoroethane; Pentafluoroethoxyethane; 2,2,2-Trifluoroethyl 2,2,2-trifluoroethyl ether (unsymmetrical); EINECS 244-747-3; HFE-245mc (industry code)
EINECS	244-747-3

Quality Control

Our Pentafluoroethyl Ethyl Ether is produced under stringent quality management systems. Each batch is analyzed to ensure it meets precise chemical and physical specifications, with purity typically exceeding 98% (GC). A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile nature, store in a cool, well-ventilated area away from heat and ignition sources. Recommended storage temperature is between 2°C and 8°C to minimize evaporation and maintain stability. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.25 g/mL
Boiling Point	~40-45°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.