Description

Dimethyl Isopropylidenemalonate is a versatile malonate ester derivative characterized by its reactive isopropylidene group. This compound serves as a critical high-purity building block in advanced organic synthesis, enabling the efficient construction of complex molecular frameworks. It is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable intermediates for active ingredient development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex carboxylic acid or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where the malonate moiety is required.
• Fine Chemical Production: Serves as a versatile reagent for Knoevenagel condensations and Michael addition reactions to create specialty polymers and additives.
• Research & Development: A valuable tool in academic and industrial R&D labs for methodological development and exploring new synthetic pathways.
• Dye and Pigment Manufacturing: Intermediate in the synthesis of complex organic colorants and photostable pigments.
• Flavor and Fragrance Industry: Building block for synthesizing specific ester compounds used in high-value aroma chemicals.

Basic Information

Product Name	Dimethyl Isopropylidenemalonate
CAS No.	22035-53-6
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	Dimethyl 2-(propan-2-ylidene)malonate; Isopropylidenemalonic Acid Dimethyl Ester; Propanedioic acid, 2-(1-methylethylidene)-, dimethyl ester; Dimethyl 2-isopropylidenemalonate; 2-Isopropylidenemalonic acid dimethyl ester
EINECS	244-734-5

Quality Control

Our Dimethyl Isopropylidenemalonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed due to sensitivity to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.455
Density (20°C)	1.08 - 1.12 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.