Description

Methyl 3-(4-Methylphenyl)-3-Oxopropanoate is a high-purity organic ester compound, serving as a versatile and critical building block in advanced chemical synthesis. Its value lies in its β-ketoester functionality, which is essential for constructing complex molecular frameworks through reactions like the Michael addition, Claisen condensation, and heterocycle formation. This intermediate is particularly needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the production of various drug candidates and active pharmaceutical ingredients (APIs), particularly those containing substituted aromatic and heterocyclic systems.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides, leveraging its reactivity to create complex bioactive molecules.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and performance chemicals where specific aromatic-keto architectures are required.
• Academic & Industrial Research: A valuable reagent in organic chemistry research for methodology development and the synthesis of novel compounds for material science.
• Flavor & Fragrance Ingredient Synthesis: Employed in the controlled synthesis of aromatic compounds used in creating specific scent and flavor profiles.

Basic Information

Product Name	Methyl 3-(4-Methylphenyl)-3-Oxopropanoate
CAS No.	22027-51-6
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	Methyl 4-Methylbenzoylacetate; Methyl (4-Methylbenzoyl)acetate; 3-Oxo-3-(p-tolyl)propanoic acid methyl ester; Methyl p-Toluoylacetate; 4-Methylbenzoylacetic acid methyl ester; Acetic acid, (4-methylbenzoyl)-, methyl ester; Methyl 3-oxo-3-(4-methylphenyl)propanoate
EINECS	Contact for details

Quality Control

Our Methyl 3-(4-Methylphenyl)-3-Oxopropanoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.