Description

1-Azido-3-(Trifluoromethyl)Benzene Solution is a specialized aromatic azide derivative, valued for its unique reactivity profile as a versatile click chemistry reagent. This compound is essential for researchers and manufacturers requiring efficient, high-yield conjugation and labeling reactions under mild conditions. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and materials science for the functionalization of polymers and biomolecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those incorporating trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Click Chemistry Reagent: Enables efficient, copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation, polymer modification, and surface functionalization.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the azido and trifluoromethyl functionalities contribute to specific biological activity.
• Materials Science: Facilitates the creation of functionalized polymers, dendrimers, and advanced materials with tailored properties for electronics and coatings.
• Bioconjugation & Probe Development: Serves as a linker for attaching fluorescent dyes, affinity tags, or other probes to proteins, antibodies, and nucleic acids for diagnostic and research applications.
• Chemical Biology Research: A critical tool for activity-based protein profiling (ABPP) and the study of biomolecular interactions in living systems.

Basic Information

Product Name	1-Azido-3-(Trifluoromethyl)Benzene Solution
CAS No.	22001-17-8
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	3-(Trifluoromethyl)phenyl azide; 3-Azidobenzotrifluoride; m-(Trifluoromethyl)phenyl azide; 1-Azido-3-trifluoromethylbenzene; α,α,α-Trifluoro-m-azidotoluene; Azidobenzotrifluoride; 3-Trifluoromethylphenyl azide; (Trifluoromethyl)phenyl azide
EINECS	Contact for details

Quality Control

Our 1-Azido-3-(Trifluoromethyl)Benzene Solution is produced under stringent quality management systems to ensure batch-to-batch consistency and reliability for your critical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials. Due to its light-sensitive nature, solutions should be handled under subdued lighting conditions where practical.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Solvent Content (GC)	Specified on COA
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.