Description

2-(Chloromethoxy)-1,1,1-Trifluoroethane is a specialized fluorinated organic compound that serves as a valuable intermediate and reagent in advanced chemical synthesis. Its unique structure, featuring both a chloromethoxy and a trifluoroethyl group, makes it a versatile building block for introducing fluorinated motifs into target molecules. This compound is primarily sought by research and development laboratories, as well as production facilities in the pharmaceutical and agrochemical sectors, for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs), where the trifluoroethyl group can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging fluorine's properties to improve efficacy and environmental profile.
• Organic Synthesis Reagent: Acts as an electrophilic reagent for introducing the -CH2OCH2CF3 moiety into complex organic molecules in research settings.
• Material Science Precursor: Employed in the development of specialty polymers and coatings where fluorinated segments impart desired properties like chemical resistance or low surface energy.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on new methodologies in fluorination and the exploration of structure-activity relationships.

Basic Information

Product Name	2-(Chloromethoxy)-1,1,1-Trifluoroethane
CAS No.	21937-47-3
Molecular Formula	C3H4ClF3O
Molecular Weight	148.51 g/mol
Synonyms	1,1,1-Trifluoro-2-(chloromethoxy)ethane; 2-Chloromethoxy-1,1,1-trifluoroethane; Chloromethyl 2,2,2-trifluoroethyl ether; (2,2,2-Trifluoroethoxy)methyl chloride; α-(Chloromethoxy)-2,2,2-trifluoroethane; Trifluoroethyl chloromethyl ether
EINECS	Contact for details

Quality Control

Our 2-(Chloromethoxy)-1,1,1-Trifluoroethane is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. For projects requiring specific regulatory support, we can discuss compliance with relevant guidelines and the availability of custom analytical testing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and strong oxidizing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.