Description

3-Azido-3-Deoxy-1,2:5,6-Di-o-Isopropylidene-α-D-Allofuranose is a high-purity, protected carbohydrate derivative featuring a strategically positioned azido functional group. This compound is a critical chiral building block and versatile intermediate in synthetic organic chemistry, enabling the efficient construction of complex bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries for the development of nucleoside analogs, glycoconjugates, and other fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Glycochemistry Building Block: Used for the preparation of modified sugars and complex carbohydrate structures in glycobiology research.
• Click Chemistry Substrate: The azido group readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for bioconjugation and polymer functionalization.
• Agrochemical Synthesis: Serves as an intermediate in the development of new active ingredients with specific stereochemical requirements.
• Chemical Biology Probes: Enables the creation of labeled or tagged carbohydrate probes for studying biological recognition and metabolic pathways.
• Academic & R&D: Essential reagent for methodological development in synthetic organic chemistry and asymmetric synthesis.

Basic Information

Product Name	3-Azido-3-Deoxy-1,2:5,6-Di-o-Isopropylidene-α-D-Allofuranose
CAS No.	21870-78-0
Molecular Formula	C12H17N3O5
Molecular Weight	283.28 g/mol
Synonyms	3-Azido-3-deoxy-1,2:5,6-di-O-isopropylidene-α-D-allofuranose; 1,2:5,6-Di-O-isopropylidene-3-azido-3-deoxy-α-D-allofuranose; 3-Azido-1,2:5,6-di-O-isopropylidene-α-D-allofuranose; 3-Azido-3-deoxy-1,2:5,6-di-O-(1-methylethylidene)-α-D-allofuranose; 3-Deoxy-3-azido-1,2:5,6-di-O-isopropylidene-α-D-allofuranose; α-D-Allofuranose, 3-azido-3-deoxy-1,2:5,6-di-O-isopropylidene-
EINECS	Contact for details

Quality Control

Our 3-Azido-3-Deoxy-1,2:5,6-Di-o-Isopropylidene-α-D-Allofuranose is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support cGMP and ISO compliant production for advanced research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation [α]²⁰D	-30° to -35° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.