Description

Ethyl 2-Bromo-2-Cyclobutylacetate is a versatile brominated ester building block of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive α-bromo ester moiety adjacent to a strained cyclobutyl ring, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring cyclobutane ring systems or functionalized acetic acid derivatives.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the bromine atom serves as a handle for further functionalization.
• Organic Synthesis Reagent: Serves as an electrophile in alkylation reactions or as a precursor for generating stabilized carbanions in C-C bond-forming reactions.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Useful for synthesizing activity-based probes or labeled compounds for studying biological mechanisms.

Basic Information

Product Name	Ethyl 2-Bromo-2-Cyclobutylacetate
CAS No.	21816-22-8
Molecular Formula	C8H13BrO2
Molecular Weight	221.09 g/mol
Synonyms	2-Bromo-2-cyclobutylacetic acid ethyl ester; Ethyl α-bromo-α-cyclobutylacetate; Acetic acid, 2-bromo-2-cyclobutyl-, ethyl ester; Ethyl (2-bromo-2-cyclobutyl)acetate; α-Bromo-α-cyclobutylacetic Acid Ethyl Ester; Cyclobutanebromoacetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-2-Cyclobutylacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assessment and identity confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.