Description

(8,8-Dimethyl-8-Azoniabicyclo[3.2.1]Oct-3-Yl) 2-Hydroxy-2,2-Diphenyl-Acetate Iodide is a quaternary ammonium salt derivative of tropane, primarily recognized for its potent anticholinergic and antimuscarinic activity. This compound is of significant interest in pharmaceutical research and development, particularly for its structural role as a precursor or analog in the synthesis of active pharmaceutical ingredients (APIs). It is essential for B2B buyers in the fine chemical and pharmaceutical sectors seeking high-purity intermediates for advanced drug discovery, process development, and analytical reference standards.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of anticholinergic and antispasmodic drug candidates.
• Biochemical Research: Used as a reference standard or tool compound in pharmacological studies targeting muscarinic acetylcholine receptors.
• Process Chemistry: Serves as a critical intermediate in the scalable production of complex tropane alkaloid derivatives.
• Analytical Standard: Provides a certified reference material for quality control and method validation in pharmaceutical analysis (HPLC, GC-MS).
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) of neuroactive compounds.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(8,8-Dimethyl-8-Azoniabicyclo[3.2.1]Oct-3-Yl) 2-Hydroxy-2,2-Diphenyl-Acetate Iodide
CAS No.	21735-94-4
Molecular Formula	C25H30INO3
Molecular Weight	511.42 g/mol
Synonyms	3-Tropanyl 2-Hydroxy-2,2-diphenylacetate Iodide; 3α-Tropanyl 2-Hydroxy-2,2-diphenylacetate Iodide; Tropine 2-Hydroxy-2,2-diphenylacetate Iodide; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 2-hydroxy-2,2-diphenylacetate iodide; Diphenylglycolic Acid Tropine Ester Iodide; Tropine Benzilate Iodide; 21735-94-4; Tropanyl diphenylglycolate iodide
EINECS	Contact for details

Quality Control

Our production of (8,8-Dimethyl-8-Azoniabicyclo[3.2.1]Oct-3-Yl) 2-Hydroxy-2,2-Diphenyl-Acetate Iodide adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing results from HPLC, NMR, and mass spectrometry analyses. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.