Description

L-Threonolactone is a versatile chiral building block and heterocyclic compound of significant importance in fine chemical synthesis. Its lactone structure makes it a valuable precursor for the production of pharmaceuticals, agrochemicals, and advanced materials. This compound is particularly sought after by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various therapeutic agents, including antibiotics, antivirals, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its stereochemistry for targeted biological activity.
• Fine Chemical Production: Serves as a building block for flavors, fragrances, and other specialty organic compounds requiring high purity and specific stereoconfiguration.
• Biochemical Research: Employed in academic and industrial R&D for studying enzymatic reactions, metabolic pathways, and as a standard in analytical chemistry.
• Polymer Chemistry: Acts as a monomer or modifier for creating specialized biodegradable or functional polymers.
• Cosmetic Ingredient Synthesis: Utilized in the production of certain high-value cosmetic actives where purity and safety are paramount.

Basic Information

Product Name	L-Threonolactone
CAS No.	21730-93-8
Molecular Formula	C₄H₇NO₃
Molecular Weight	117.10 g/mol
Synonyms	(2S,3S)-2-Amino-3-hydroxybutanoic acid γ-lactone; L-2-Amino-3-hydroxybutyrolactone; L-Threonine lactone; (3S,4S)-3-Amino-4-hydroxydihydrofuran-2(3H)-one; L-α-Amino-β-hydroxybutyrolactone; L-Threonic acid lactone; 3-Amino-4-hydroxybutanoic acid lactone; L-3-Amino-4-hydroxybutyric acid γ-lactone
EINECS	244-548-9

Quality Control

Our L-Threonolactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to guarantee supply consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.