Description

Methyl D-Alaninate is a high-purity, non-natural enantiomer of the amino acid derivative alanine methyl ester. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients, peptides, and chiral catalysts. Its defined configuration ensures reproducibility in processes requiring specific optical activity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and antibiotic research.
• Peptide Synthesis: Used as a protected D-amino acid derivative in solid-phase and solution-phase peptide synthesis to incorporate D-alanine residues.
• Agrochemical Development: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Catalyst and Ligand Preparation: Employed in the synthesis of chiral catalysts and ligands for asymmetric synthesis applications.
• Biochemical Research: Utilized in enzymatic studies and as a substrate analog to investigate enzyme specificity and mechanism.
• Food & Flavor Industry: Potential intermediate for synthesizing certain non-natural flavor compounds or sweeteners.

Basic Information

Product Name	Methyl D-Alaninate
CAS No.	21705-13-5
Molecular Formula	C4H9NO2
Molecular Weight	103.12 g/mol
Synonyms	D-Alanine methyl ester; Methyl (R)-2-aminopropanoate; (R)-2-Aminopropionic acid methyl ester; D-2-Aminopropanoic acid methyl ester; (R)-Alanine methyl ester; Methyl ester of D-alanine; D-Ala-OMe; (R)-Methyl alaninate
EINECS	244-525-0

Quality Control

Our Methyl D-Alaninate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific rotation are provided with every shipment. We support compliance with cGMP, ISO, and REACH frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (D-isomer)
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.