Description

tert-Butyl L-alaninate is a protected amino acid ester derivative, serving as a crucial chiral building block in advanced organic synthesis. Its primary value lies in providing a sterically hindered tert-butyl ester group, which offers enhanced stability under various reaction conditions while remaining readily cleavable under acidic treatment. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require high-purity intermediates for peptide synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of complex peptides, peptidomimetics, and novel drug candidates.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce the L-alanine residue with a protected carboxyl group.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in catalytic asymmetric reactions due to its well-defined stereochemistry.
• Bioconjugation: Useful in the preparation of modified biomolecules and drug-linker complexes for targeted therapies.
• Agrochemical Research: Intermediate in the development of chiral pesticides and herbicides.
• Academic & R&D: Serves as a standard or reagent in methodological development and chemical biology studies.

Basic Information

Product Name	tert-Butyl L-alaninate
CAS No.	21691-50-9
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	L-Alanine tert-butyl ester; (S)-2-((tert-Butoxycarbonyl)amino)propanoic acid; Boc-L-Ala-OtBu; (S)-tert-Butyl 2-aminopropanoate; H-Ala-OtBu; Alanine, N-Boc-, tert-butyl ester; tert-Butyl (S)-2-aminopropanoate; 2-Aminopropanoic acid, 1,1-dimethylethyl ester, (S)-
EINECS	Contact for details

Quality Control

Our tert-Butyl L-alaninate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing identity, assay, enantiomeric excess, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.