Description

1,2-Dihydrocyclobuta[B]Quinoline-8-Carboxylic Acid Methyl Ester is a high-purity, synthetically derived organic compound that serves as a critical advanced intermediate in modern chemical synthesis. Its unique fused ring structure makes it a valuable building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers requiring a reliable, high-quality precursor for active pharmaceutical ingredient (API) development and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel quinoline-based drug candidates, including potential anti-malarial, anti-cancer, and anti-inflammatory agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organic Synthesis & Material Science: Serves as a versatile precursor for creating complex polycyclic aromatic structures used in organic light-emitting diodes (OLEDs) and other advanced materials.
• Academic & R&D Laboratories: Employed in methodological studies and as a reference standard for reaction development and analytical chemistry.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty dyes, pigments, and photostabilizers.

Basic Information

Product Name	1,2-Dihydrocyclobuta[B]Quinoline-8-Carboxylic Acid Methyl Ester
CAS No.	21691-02-1
Molecular Formula	C₁₃H₁₁NO₂
Molecular Weight	213.23 g/mol
Synonyms	Methyl 1,2-dihydrocyclobuta[b]quinoline-8-carboxylate; 8-Quinolinecarboxylic acid, 1,2-dihydrocyclobuta[b]-, methyl ester; Cyclobuta[b]quinoline-8-carboxylic acid, 1,2-dihydro-, methyl ester; Methyl 1,2-dihydrocyclobuta[b]quinoline-8-carboxylate; 21691-02-1; 1,2-Dihydrocyclobuta[b]quinoline-8-methyl carboxylate
EINECS	Contact for details

Quality Control

Our production of 1,2-Dihydrocyclobuta[B]Quinoline-8-Carboxylic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, identity, and impurity profiles via validated methods such as HPLC, GC, and NMR. Our quality system is designed to support cGMP compliance for pharmaceutical applications, and we can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.