Description

[4-[Bis(2-Chloroethyl)Amino]Phenyl] 2-Methylbenzoate CAS NO 21667-00-5 is a specialized nitrogen mustard derivative ester compound with significant research and development applications. This chemical is valued for its role as a key synthetic intermediate in the development of novel pharmaceutical agents and biochemical probes. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, oncology research, and the synthesis of targeted therapeutic compounds. Its unique structure makes it a critical building block for advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of experimental nitrogen mustard-based chemotherapeutic agents and targeted drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of novel alkylating agents for oncology and other therapeutic areas.
• Biochemical Probe Development: Acts as a scaffold for creating labeled compounds or conjugates used to study biological pathways and enzyme interactions.
• Organic Synthesis Building Block: Employed in advanced organic synthesis for constructing complex molecules with specific pharmacological properties.
• Academic and Industrial R&D: Utilized in university laboratories and corporate R&D centers for exploratory chemistry and new compound library generation.

Basic Information

Product Name	[4-[Bis(2-Chloroethyl)Amino]Phenyl] 2-Methylbenzoate
CAS No.	21667-00-5
Molecular Formula	C20H23Cl2NO2
Molecular Weight	380.31 g/mol
Synonyms	o-Toluic acid, 4-[bis(2-chloroethyl)amino]phenyl ester; 4-[Bis(2-chloroethyl)amino]phenyl 2-methylbenzoate; Phenyl 2-methylbenzoate, 4-[bis(2-chloroethyl)amino]-; 2-Methylbenzoic acid 4-[bis(2-chloroethyl)amino]phenyl ester; NSC 176323; Mustard phenyl o-toluate derivative
EINECS	Contact for details

Quality Control

Our [4-[Bis(2-Chloroethyl)Amino]Phenyl] 2-Methylbenzoate is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.