Description

Diisopropyl Cyanomethylphosphonate is a specialized organophosphorus compound with the CAS number 21658-95-7, serving as a versatile building block in advanced organic synthesis. Its unique structure, featuring both phosphonate and nitrile functional groups, makes it a critical reagent for constructing complex molecular frameworks. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its phosphonate moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized phosphine-based ligands used in asymmetric catalysis and transition metal complexes.
• Flame Retardant Additive Research: Investigated as a potential component in the development of new, more efficient flame-retardant formulations for polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of activity-based probes for studying enzyme function and mechanism.
• Material Science: Employed in the synthesis of functionalized monomers and polymers with tailored properties for advanced materials.

Basic Information

Product Name	Diisopropyl Cyanomethylphosphonate
CAS No.	21658-95-7
Molecular Formula	C8H16NO3P
Molecular Weight	205.19 g/mol
Synonyms	Cyanomethylphosphonic Acid Diisopropyl Ester; Diisopropyl (Cyanomethyl)phosphonate; Phosphonic Acid, (Cyanomethyl)-, Diisopropyl Ester; (Cyanomethyl)phosphonic Acid Diisopropyl Ester; Diisopropyl Cyanomethyl Phosphonate; Isopropyl Cyanomethylphosphonate; Cyanomethyl-diisopropylphosphonate; Diisopropyl Pocyanomethylphosphonate
EINECS	244-525-9

Quality Control

Our Diisopropyl Cyanomethylphosphonate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including NMR, HPLC, and GC analysis, to verify identity, potency, and impurity profiles. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Specific Gravity (20°C)	1.080 - 1.120
Refractive Index (20°C)	1.430 - 1.450

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.