Description

(S)-Methyl 5-Oxotetrahydrofuran-2-Carboxylate is a high-value chiral building block and intermediate of significant importance in advanced organic synthesis. This compound matters because its stereochemistry and functional groups make it a versatile precursor for synthesizing complex, optically active molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various bioactive molecules and Active Pharmaceutical Ingredients (APIs).
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to construct complex stereocenters.
• Lactone & Furan Chemistry: Serves as a precursor for the preparation of substituted lactones and furan derivatives with specific stereochemistry.
• Agrochemical Research: Employed in the development of chiral pesticides and herbicides.
• Material Science: Potential monomer or intermediate for synthesizing specialty polymers with unique properties.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research.

Basic Information

Product Name	(S)-Methyl 5-Oxotetrahydrofuran-2-Carboxylate
CAS No.	21461-85-8
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	(S)-(-)-Methyl 5-oxo-2-tetrahydrofurancarboxylate; (S)-Methyl tetrahydro-5-oxo-2-furancarboxylate; (S)-Methyl 2,5-dihydro-5-oxofuran-2-carboxylate; Methyl (S)-5-oxotetrahydrofuran-2-carboxylate; (S)-5-Oxotetrahydro-2-furancarboxylic acid methyl ester; L-(-)-Methyl 5-oxo-2-tetrahydrofurancarboxylate
EINECS	Contact for details

Quality Control

Our (S)-Methyl 5-Oxotetrahydrofuran-2-Carboxylate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.