Description

(1S,3Aβ,6Aβ)-Tetrahydro-1β,4α-Bis(3,5-Dimethoxy-4-Hydroxyphenyl)-1H,3H-Furo[3,4-C]Furan is a complex, high-purity lignan derivative with a unique furofuran core structure. This compound matters as a critical advanced pharmaceutical intermediate and a valuable reference standard for analytical and research applications. It is primarily needed by manufacturers and R&D teams in the pharmaceutical, nutraceutical, and fine chemical sectors for the development of novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and metabolic disease research.
• Reference Standard: High-purity material for analytical method development, validation, and quality control (QC/QA) in pharmaceutical laboratories.
• Biochemical Research: Used as a probe or substrate in enzymatic studies and for investigating biological pathways related to its structural activity.
• Natural Product Synthesis: Serves as a sophisticated precursor in the total synthesis of complex natural products and lignan analogs.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations due to its polyphenolic antioxidant structure.

Basic Information

Product Name	(1S,3Aβ,6Aβ)-Tetrahydro-1β,4α-Bis(3,5-Dimethoxy-4-Hydroxyphenyl)-1H,3H-Furo[3,4-C]Furan
CAS No.	21453-71-4
Molecular Formula	C22H26O8
Molecular Weight	418.44 g/mol
Synonyms	1H,3H-Furo[3,4-c]furan, tetrahydro-1,4-bis(3,5-dimethoxy-4-hydroxyphenyl)-, (1S,3aβ,6aβ)-; (-)-Syringaresinol; L-Syringaresinol; Syringaresinol; Furo[3,4-c]furan, tetrahydro-1,4-bis(3,5-dimethoxy-4-hydroxyphenyl)-, (1S,3aβ,6aβ)-; Lirioresinol B; Eleutheroside E
EINECS	Contact for details

Quality Control

Our (1S,3Aβ,6Aβ)-Tetrahydro-1β,4α-Bis(3,5-Dimethoxy-4-Hydroxyphenyl)-1H,3H-Furo[3,4-C]Furan is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC purity assay, chiral purity verification, and identity confirmation, to ensure it meets exacting standards for research and production. Comprehensive Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.