Description

(+)-Epinephrine(-)-Bitartrate is a high-purity, enantiomerically pure salt form of the critical neurotransmitter and hormone epinephrine. This compound is essential for its potent and specific pharmacological activity as a sympathomimetic agent, primarily targeting adrenergic receptors. It is a fundamental active pharmaceutical ingredient (API) and research chemical for the development and production of emergency medications, ophthalmic solutions, and advanced cardiovascular research. Global pharmaceutical manufacturers, analytical laboratories, and R&D institutions rely on this material for its consistent quality and biological specificity.

Application

• Active Pharmaceutical Ingredient (API) in injectable formulations for emergency treatment of anaphylaxis, cardiac arrest, and severe asthma attacks.
• Ophthalmic Solution Production for use in glaucoma treatment and during ocular surgery to induce mydriasis (pupil dilation) and control bleeding.
• Biochemical Research & Development as a standard and tool compound for studying adrenergic receptor signaling, cardiovascular physiology, and metabolic pathways.
• Analytical Reference Standard for quality control testing in pharmaceutical manufacturing, ensuring product potency and purity via HPLC, GC, or titration methods.
• Veterinary Medicine for emergency resuscitation and as a vasoconstrictor in surgical procedures for animals.
• Formulation Development for stable drug delivery systems, investigating compatibility with various excipients and packaging materials.

Basic Information

Product Name	(+)-Epinephrine(-)-Bitartrate
CAS No.	21282-30-4
Molecular Formula	C9H13NO3 • C4H6O6
Molecular Weight	333.29 g/mol
Synonyms	L-Epinephrine Bitartrate; (-)-Epinephrine Bitartrate; Adrenaline Bitartrate; (R)-(-)-Epinephrine Bitartrate; 1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol Bitartrate; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol Bitartrate; Levorenium Bitartrate; Adrenaline Acid Tartrate
EINECS	244-295-3

Quality Control

Our (+)-Epinephrine(-)-Bitartrate is manufactured and tested under strict quality management systems. It is typically produced to meet or exceed relevant pharmacopoeial standards such as USP and EP monographs, ensuring suitability for pharmaceutical applications. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our rigorous quality testing protocols include advanced chromatographic and spectroscopic methods to guarantee batch-to-batch consistency and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified. This material is strictly light-sensitive and easily oxidized; it must be stored under an inert atmosphere (e.g., nitrogen or argon) in its original sealed packaging to prevent degradation. Keep the container in a dry, cool, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Specific Rotation [α]20/D	-50.0° to -53.5° (c = 2 in water)
Water (KF Titration)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.