Description

4-(Benzyloxy)Butyric Acid Trimethylsilyl Ester is a valuable organosilicon-protected intermediate used in advanced organic synthesis. This compound is specifically designed to act as a protected carboxylic acid derivative, offering enhanced stability and reactivity control during complex chemical transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of potential drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a protected carboxyl component in peptide coupling reactions and solid-phase peptide synthesis (SPPS).
• Material Science Research: Intermediate for creating functionalized polymers, dendrimers, and advanced organic materials.
• Asymmetric Synthesis: Employed in stereoselective reactions to construct chiral centers in complex molecular architectures.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling protocols.

Basic Information

Product Name	4-(Benzyloxy)Butyric Acid Trimethylsilyl Ester
CAS No.	21273-17-6
Molecular Formula	C14H22O3Si
Molecular Weight	266.41 g/mol
Synonyms	4-(Benzyloxy)butanoic Acid Trimethylsilyl Ester; Trimethylsilyl 4-(Benzyloxy)butanoate; 4-(Benzyloxy)butyric Acid TMS Ester; Butanoic Acid, 4-(Phenylmethoxy)-, Trimethylsilyl Ester; TMS 4-(Benzyloxy)butyrate; 21273-17-6; 4-(Benzyloxy)butyric Acid Trimethylsilyl Ester
EINECS	Contact for details

Quality Control

Our production of 4-(Benzyloxy)Butyric Acid Trimethylsilyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including chromatographic purity assessment and structural confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality management and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. Due to its sensitivity to moisture and potential hydrolysis, containers should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.