Description

3-Phenylpropanoic Acid Trimethylsilyl Ester is a versatile organosilicon derivative of hydrocinnamic acid, valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis. Its primary commercial value lies in enhancing process efficiency and enabling complex molecular constructions that are difficult to achieve with the parent carboxylic acid. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where precise control over synthetic pathways is critical.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring temporary protection of the carboxylic acid functionality during multi-step reactions.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Precursor: Acts as a protected form of hydrocinnamic acid for the controlled synthesis of aromatic esters and other compounds used in perfumery.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, Grignard additions, and other transformations where the silyl ester offers superior reactivity or stability over the free acid.
• Material Science Research: Utilized in the development of novel polymers and organic-inorganic hybrid materials where the phenylpropanoate moiety is incorporated.
• Analytical Reference Standard: Provided as a high-purity standard for gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) analysis in quality control and research laboratories.

Basic Information

Product Name	3-Phenylpropanoic Acid Trimethylsilyl Ester
CAS No.	21273-15-4
Molecular Formula	C12H18O2Si
Molecular Weight	222.36 g/mol
Synonyms	Hydrocinnamic Acid Trimethylsilyl Ester; Trimethylsilyl 3-Phenylpropanoate; 3-Phenylpropionic Acid TMS Ester; TMS Hydrocinnamate; β-Phenylpropionic Acid Trimethylsilyl Ester; (3-Phenylpropanoyloxy)trimethylsilane; Trimethylsilyl β-phenylpropionate; Phenylpropanoic Acid TMS Ester
EINECS	Contact for details

Quality Control

Our 3-Phenylpropanoic Acid Trimethylsilyl Ester is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.