Description

Butyric Acid, 4-Phenoxy-, Trimethylsilyl Ester is a specialized organosilicon derivative of phenoxybutyric acid, serving as a key protected intermediate in advanced organic synthesis. This compound is valued for its role in introducing the phenoxybutyryl moiety under mild conditions, enabling the synthesis of complex molecules with high selectivity. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the production of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a protected phenoxybutyric acid functionality.
• Agrochemical Synthesis: Serves as a building block for creating herbicides, fungicides, and plant growth regulators with specific phenoxy chain modifications.
• Peptide Chemistry: Acts as a reagent for the temporary protection of carboxylic acid groups during complex peptide coupling sequences.
• Material Science Research: Employed in the development of novel silicon-containing polymers and hybrid organic-inorganic materials.
• Chemical Derivatization: Utilized in analytical chemistry for the silylation of sensitive compounds to improve their volatility for GC-MS analysis.
• Academic & Industrial R&D: A valuable tool for method development and exploratory synthesis in medicinal chemistry and chemical biology.

Basic Information

Product Name	Butyric Acid, 4-Phenoxy-, Trimethylsilyl Ester
CAS No.	21273-10-9
Molecular Formula	C13H20O3Si
Molecular Weight	252.38 g/mol
Synonyms	4-Phenoxybutyric Acid Trimethylsilyl Ester; Trimethylsilyl 4-Phenoxybutanoate; γ-Phenoxybutyric Acid Trimethylsilyl Ester; Butanoic Acid, 4-Phenoxy-, Trimethylsilyl Ester; TMS 4-Phenoxybutyrate; Silylating Agent S-4; (4-Phenoxybutanoyloxy)trimethylsilane; 21273-10-9
EINECS	Contact for details

Quality Control

Our Butyric Acid, 4-Phenoxy-, Trimethylsilyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and industrial use. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.