Description

3-Phenoxypropionic Acid Trimethylsilyl Ester is a specialized organosilicon derivative of phenoxypropionic acid, serving as a valuable protected intermediate and derivatization agent in advanced organic synthesis. Its primary value lies in its ability to act as a silylating reagent, protecting carboxylic acid groups and enhancing the volatility of analytes for gas chromatography. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, where precise synthetic manipulation and analytical method development are critical.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and complex drug molecules, particularly where carboxylic acid protection is required.
• Agrochemical Synthesis: Serves as a key building block in the production of advanced herbicides, insecticides, and plant growth regulators.
• Analytical Derivatization Agent: Employed in Gas Chromatography (GC) and GC-MS to derivative carboxylic acids, improving their thermal stability and detection sensitivity.
• Fine Chemical Production: A crucial reagent for the preparation of specialty chemicals, flavors, fragrances, and advanced material precursors.
• Organic Synthesis Research: Utilized in academic and industrial R&D labs for method development, protecting group chemistry, and exploring new reaction pathways.
• Silicon Chemistry: Acts as a model compound or reagent in studies involving organosilicon chemistry and silylation techniques.

Basic Information

Product Name	3-Phenoxypropionic Acid Trimethylsilyl Ester
CAS No.	21273-09-6
Molecular Formula	C12H18O3Si
Molecular Weight	238.36 g/mol
Synonyms	Trimethylsilyl 3-phenoxypropionate; 3-Phenoxypropanoic Acid Trimethylsilyl Ester; Propanoic acid, 3-phenoxy-, trimethylsilyl ester; TMS 3-Phenoxypropionate; Phenoxypropionic Acid TMS Ester; 3-Phenoxypropionic Acid TMS; Trimethylsilyl 3-phenoxypropanoate
EINECS	Contact for details

Quality Control

Our 3-Phenoxypropionic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of research and industrial-scale manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.