Description

Methyl 3-Bromobutyrate CAS NO 21249-59-2 is a versatile brominated ester building block, essential for introducing the 3-bromobutyl moiety in complex organic syntheses. Its reactive bromine and ester functionalities make it a critical intermediate for constructing pharmaceuticals, agrochemicals, and advanced materials. This high-purity compound is primarily sought by R&D chemists and process development teams in the pharmaceutical, fine chemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a functionalized butyric acid side chain.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the bromine atom serves as a reactive handle for further derivatization.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty esters through subsequent hydrolysis, reduction, or cross-coupling reactions.
• Polymer & Material Science: Acts as a monomer or chain-transfer agent in the synthesis of specialty polymers and functional materials.
• Organic Synthesis Reagent: Employed in nucleophilic substitution reactions, Grignard reagent formation, and palladium-catalyzed cross-couplings like Suzuki or Heck reactions.
• Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Item	Details
Product Name	Methyl 3-Bromobutyrate
CAS No.	21249-59-2
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	3-Bromobutanoic Acid Methyl Ester; Methyl 3-Bromobutanoate; 3-Bromobutyric Acid Methyl Ester; β-Bromobutyric Acid Methyl Ester; Methyl β-Bromobutyrate; Butanoic acid, 3-bromo-, methyl ester; NSC 404087
EINECS	244-310-9

Quality Control

Our production of Methyl 3-Bromobutyrate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like GC, HPLC, and NMR to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Refractive Index (n20D)	1.4580 - 1.4620
Density (g/mL, 20°C)	1.420 - 1.440
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.