Description

Epinephrine Sulfate is a stable, water-soluble salt form of the critical endogenous hormone and neurotransmitter epinephrine. This compound is essential for its potent vasoconstrictive and bronchodilatory effects, making it a cornerstone in emergency medical protocols. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of life-saving injectable formulations, such as those used to treat severe allergic reactions (anaphylaxis), cardiac arrest, and acute asthma attacks. The product referenced as CAS NO 21093-18-5 is supplied to meet the stringent demands of these high-stakes applications.

Application

• Pharmaceutical Active Ingredient (API): Core component in the manufacture of emergency injectable drugs, including auto-injectors (e.g., EpiPen equivalents) and ampoules for hospital use.
• Anaphylaxis Treatment: Formulated into solutions for the rapid reversal of severe allergic reactions, providing immediate vasoconstriction and bronchodilation.
• Cardiac Resuscitation: Used in advanced cardiac life support (ACLS) protocols as a key agent to stimulate cardiac activity during cardiopulmonary resuscitation (CPR).
• Local Anesthetic Adjuvant: Added to local anesthetics (e.g., in dental procedures) to prolong their effect by constricting blood vessels and reducing systemic absorption.
• Ophthalmic Solutions: Employed in certain ophthalmic preparations to manage intraocular pressure and induce mydriasis (pupil dilation).
• Biochemical Research: Used as a standard and reagent in pharmacological and physiological studies investigating adrenergic receptor function and signal transduction pathways.
• Veterinary Medicine: Critical for emergency treatment of anaphylaxis and cardiac support in veterinary practice.

Basic Information

Product Name	Epinephrine Sulfate
CAS No.	21093-18-5
Molecular Formula	C9H13NO3 · H2SO4
Molecular Weight	328.33 g/mol (for the sulfate salt)
Synonyms	Adrenaline Sulfate; (-)-Epinephrine Sulfate; L-Epinephrine Sulfate; 1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol Sulfate; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol Sulfate; Adrenaline Acid Sulfate; Suprarenin Sulfate
EINECS	244-209-3

Quality Control

Our Epinephrine Sulfate is manufactured and tested under strict quality management systems to ensure it meets the high-purity standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing critical parameters such as assay, related substances, residual solvents, and microbiological quality. We can supply material compliant with various pharmacopeial monographs, including USP and EP, upon request. Our commitment to rigorous quality control ensures batch-to-batch consistency and supply reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being strictly light-sensitive and easily oxidized, the product must be stored under an inert atmosphere (e.g., nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2°C to 8°C. The container should be kept in a dry environment to prevent moisture uptake and clearly labeled with handling precautions.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Meets Ph. Eur. 2.6.12 / USP <61> requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.