Description

n-(1-Carboxy-L-Prolyl)-L-Valine Ethyl Methyl Ester is a high-purity, non-natural dipeptide derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex peptide frameworks and as a chiral intermediate in pharmaceutical research and development. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel peptide-based drugs and protease inhibitors.
• Bioconjugation & Peptide Engineering: Used in the design and construction of modified peptides with enhanced stability or specific biological activity.
• Medicinal Chemistry Research: Serves as a valuable building block in structure-activity relationship (SAR) studies and combinatorial chemistry libraries.
• Biochemical Tool Development: Employed in the preparation of enzyme substrates, inhibitors, or affinity ligands for biochemical assays.
• Fine Chemical Synthesis: Intermediate in the multi-step synthesis of complex organic molecules requiring specific stereochemistry.

Basic Information

Product Name	n-(1-Carboxy-L-Prolyl)-L-Valine Ethyl Methyl Ester
CAS No.	21026-88-0
Molecular Formula	C15H24N2O6
Molecular Weight	328.36 g/mol
Synonyms	L-Valine, N-[(1S)-1-(carboxy)-2-pyrrolidinyl]carbonyl]-, ethyl methyl ester; N-[(1-Carboxy-L-prolyl)]-L-valine ethyl methyl ester; Ethyl Methyl N-(1-Carboxy-L-prolyl)-L-valinate; Pro-Val-OMe-OEt; (S)-Ethyl (S)-Methyl 2-((S)-1-carboxy-2-pyrrolidinamido)-3-methylbutanoate; N-(1-Carboxyprolyl)valine ethyl methyl ester; A dipeptide derivative of L-Proline and L-Valine.
EINECS	Contact for details

Quality Control

Our n-(1-Carboxy-L-Prolyl)-L-Valine Ethyl Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.