Description

N,N,o-Tris(Trimethylsilyl)Hydroxylamine is a specialized organosilicon reagent featuring a fully silylated hydroxylamine structure. This compound is valued for its role as a versatile silylating agent and protected hydroxylamine source in advanced synthetic chemistry. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of complex molecules and functional materials.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key building block and protecting group reagent in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and insecticides that require hydroxylamine or silyl ether functionalities.
• Material Science & Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the creation of specialty silicones and silicon-containing polymers.
• Organic Synthesis Reagent: Serves as a protected source of hydroxylamine for nucleophilic reactions and as a silyl donor in functional group transformations.
• Chemical Derivatization: Utilized in analytical chemistry to derivative sensitive compounds for gas chromatography (GC) or mass spectrometry (MS) analysis.
• Academic & Industrial R&D: A critical tool for methodology development and exploratory synthesis in university and corporate research laboratories.

Basic Information

Product Name	N,N,o-Tris(Trimethylsilyl)Hydroxylamine
CAS No.	21023-20-1
Molecular Formula	C9H27NO1Si3
Molecular Weight	249.58 g/mol
Synonyms	Hydroxylamine, N,N,O-tris(trimethylsilyl)-; Tris(trimethylsilyl)hydroxylamine; N,O-Bis(trimethylsilyl)hydroxylamine, N-trimethylsilylated; TMS-hydroxylamine, per-silylated; N,N,O-Tris(trimethylsilyl)hydroxyamine; 1,1,1-Trimethyl-N-(trimethylsilyloxy)-N-(trimethylsilyl)silanamine; Hydroxylamine tris(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our N,N,o-Tris(Trimethylsilyl)Hydroxylamine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and scale-up applications. Each lot is analyzed via GC, NMR, and titration to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.