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Ethyl (2E)-3-Cyclopropylacrylate CAS NO 21014-26-6


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CAS No.:21014-26-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl (2E)-3-Cyclopropylacrylate is a high-purity, unsaturated ester monomer featuring a cyclopropyl group conjugated to an acrylate moiety. This compound is valued for its unique structural motif, which imparts specific reactivity and properties, making it a versatile building block in advanced organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediates: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the cyclopropane ring for biological activity or metabolic stability.
  • Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropylacrylate unit can contribute to potent biological activity.
  • Specialty Monomers: Acts as a functional monomer for creating polymers with tailored properties, such as modified glass transition temperatures, adhesion, or chemical resistance.
  • Fine Chemical Production: Employed in multi-step organic synthesis for producing flavors, fragrances, and other high-value fine chemicals.
  • Cross-coupling Reactions: The acrylate double bond is reactive in various metal-catalyzed cross-coupling reactions (e.g., Heck reaction) for C-C bond formation.
  • Material Science Research: Investigated for use in novel organic electronic materials or as a component in photoresists and other advanced materials.

Basic Information

Product Name Ethyl (2E)-3-Cyclopropylacrylate
CAS No. 21014-26-6
Molecular Formula C8H12O2
Molecular Weight 140.18 g/mol
Synonyms Ethyl (E)-3-Cyclopropylacrylate; (E)-Ethyl 3-Cyclopropacrylate; 2-Propenoic acid, 3-cyclopropyl-, ethyl ester, (2E)-; Ethyl trans-3-Cyclopropylacrylate; 3-Cyclopropylacrylic acid ethyl ester; trans-Ethyl 3-cyclopropylpropenoate; Ethyl 3-Cyclopropyl-2-propenoate
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Quality Control

Our Ethyl (2E)-3-Cyclopropylacrylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting exact specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality protocols to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 97.0% (Area %)
Isomeric Purity ((E)-isomer) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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