Description

n-(Ethoxyoxoacetyl)-L-Alanine Ethyl Ester is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical chiral building block, enabling the controlled introduction of the L-alanine moiety into complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development of novel peptides, active pharmaceutical ingredients (APIs), and other fine chemicals where stereochemical integrity is paramount.

Application

• Peptide Synthesis: A key protected intermediate for the solid-phase and solution-phase synthesis of custom peptides and peptidomimetics.
• Pharmaceutical Intermediates: Used in the research and production of chiral drug candidates, particularly in oncology and metabolic disease research.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Employed in the synthesis of labeled amino acids and activity-based probes for studying enzyme function and protein interactions.
• Agrochemical Research: Acts as a chiral synthon in the development of novel, biologically active compounds for crop protection.
• Material Science: Utilized in the synthesis of specialized polymers and dendrimers with tailored properties.

Basic Information

Product Name	n-(Ethoxyoxoacetyl)-L-Alanine Ethyl Ester
CAS No.	20902-48-1
Molecular Formula	C9H15NO5
Molecular Weight	217.22 g/mol
Synonyms	N-(Ethoxyoxoacetyl)-L-alanine ethyl ester; Ethyl N-(ethoxyoxoacetyl)-L-alaninate; L-Alanine, N-(ethoxyoxoacetyl)-, ethyl ester; N-Carbethoxyglycyl-L-alanine ethyl ester; Acetic acid, 2-[(1-ethoxycarbonyl)ethylamino]-2-oxo-, ethyl ester; Ethyl 2-[(1-ethoxycarbonyl)ethylamino]-2-oxoacetate; Alanine derivative, N-ethoxyoxoacetyl, ethyl ester
EINECS	Contact for details

Quality Control

Our n-(Ethoxyoxoacetyl)-L-Alanine Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.