Description

(3Ar,3Aβ,6R,7Aβ)-2,2,2',2'-Tetramethyl-3A,4,7,7A-Tetrahydrospiro[6H-1,3-Dioxolo[4,5-C]Pyran-6,4'-[1,3]Dioxolane]-7β-Ol is a high-purity, complex spirocyclic acetal derivative with a defined stereochemistry, serving as a critical chiral building block and synthetic intermediate. Its value lies in providing a rigid, functionalized molecular scaffold essential for constructing sophisticated target molecules in advanced organic synthesis. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise stereocontrol is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, anticancer, and neurological disorder research.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule influences biological activity.
• Asymmetric Catalysis: Employed as a precursor or ligand in the design of chiral catalysts for enantioselective transformations.
• Material Science: Serves as a monomer or building block for creating novel polymers with specific optical or structural properties.
• Academic & R&D Laboratories: A valuable tool for methodological studies in total synthesis and the exploration of new spirocyclic chemistry.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of complex, naturally-derived odorants and flavorants requiring specific stereochemistry.

Basic Information

Product Name	(3Ar,3Aβ,6R,7Aβ)-2,2,2',2'-Tetramethyl-3A,4,7,7A-Tetrahydrospiro[6H-1,3-Dioxolo[4,5-C]Pyran-6,4'-[1,3]Dioxolane]-7β-Ol
CAS No.	20880-93-7
Molecular Formula	C13H20O6
Molecular Weight	272.29 g/mol
Synonyms	7β-Hydroxyspiro[1,3-dioxolane-4,6'-[6H]1,3-dioxolo[4,5-c]pyran]; (3aR,3a1S,6R,7aS)-2,2,2',2'-Tetramethyl-3a,4,7,7a-tetrahydrospiro[1,3]dioxolo[4,5-c]pyran-6,4'-[1,3]dioxolane]-7β-ol; Spirocyclic Dioxolane-Dioxolopyran Derivative; 20880-93-7; 1,3-Dioxolo[4,5-c]pyran-6-ol, tetrahydro-2,2,2',2'-tetramethyl-, 4,4'-(1-methylethylidene)bis-, (3aR,3a1S,6R,7aS)-rel-
EINECS	Contact for details

Quality Control

Our (3Ar,3Aβ,6R,7Aβ)-2,2,2',2'-Tetramethyl-3A,4,7,7A-Tetrahydrospiro[6H-1,3-Dioxolo[4,5-C]Pyran-6,4'-[1,3]Dioxolane]-7β-Ol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity, NMR for structural confirmation, and standard pharmacopeial tests to ensure identity, strength, and purity. Certificates of Analysis (COA) detailing all specifications and results are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.