Description

2-O,3-O,5-O,6-o-Tetramethyl-D-Mannonic Acid γ-Lactone is a high-purity, synthetically derived chiral building block and intermediate of significant interest in advanced organic synthesis. This compound is valued for its role in the preparation of complex carbohydrates, nucleoside analogs, and other fine chemicals where precise stereochemistry is critical. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of nucleoside derivatives, antiviral agents, and other active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry Research: Essential building block for constructing complex oligosaccharides, glycoconjugates, and glycomimetics in academic and industrial R&D.
• Agrochemical Synthesis: Intermediate in the production of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of specialty surfactants, ligands for asymmetric catalysis, and advanced polymer precursors.
• Diagnostic Reagent Development: Serves as a precursor for labeled compounds and probes used in biochemical assays and diagnostic kits.

Basic Information

Product Name	2-O,3-O,5-O,6-o-Tetramethyl-D-Mannonic Acid γ-Lactone
CAS No.	20869-29-8
Molecular Formula	C10H16O6
Molecular Weight	232.23 g/mol
Synonyms	2,3,5,6-Tetra-O-methyl-D-mannono-1,4-lactone; D-Mannonic acid, 2,3,5,6-tetramethyl-, γ-lactone; Tetramethyl-D-mannonolactone; 1,4-Anhydro-2,3,5,6-tetra-O-methyl-D-mannitol; γ-Lactone of 2,3,5,6-tetra-O-methyl-D-mannonic acid; (3R,4S,5R,6R)-3,4,5,6-Tetramethoxytetrahydro-2H-pyran-2-one
EINECS	Contact for details

Quality Control

Our 2-O,3-O,5-O,6-o-Tetramethyl-D-Mannonic Acid γ-Lactone is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.