Description

(S)-Dimethyl Bromosuccinate is a high-value chiral building block and synthetic intermediate of significant importance in asymmetric organic synthesis. Its primary value lies in its ability to introduce a stereodefined succinate moiety, which is a key structural motif in many biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of active pharmaceutical ingredients (APIs) and fine chemicals requiring precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug molecules, including potential enzyme inhibitors and receptor modulators.
• Asymmetric Synthesis: Used in stereoselective reactions to construct carbon-carbon bonds and introduce chiral centers with high enantiomeric purity.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides with specific stereochemical configurations.
• Ligand and Catalyst Preparation: Employed in the synthesis of chiral ligands for transition metal catalysis and organocatalysts.
• Natural Product Synthesis: A valuable intermediate in the total synthesis of natural products containing succinate or malate derivatives.
• Polymer Chemistry: Can be used to introduce functional, chiral monomers for specialty polymer applications.

Basic Information

Product Name	(S)-Dimethyl Bromosuccinate
CAS No.	20859-24-9
Molecular Formula	C6H9BrO4
Molecular Weight	225.04 g/mol
Synonyms	(S)-Dimethyl 2-bromosuccinate; (2S)-Dimethyl 2-bromobutanedioate; (S)-2-Bromosuccinic Acid Dimethyl Ester; L-Dimethyl Bromosuccinate; Bromosuccinic Acid Dimethyl Ester, (S)-; Dimethyl (S)-(-)-2-Bromosuccinate; Butanedioic acid, 2-bromo-, 1,4-dimethyl ester, (2S)-
EINECS	Contact for details

Quality Control

Our (S)-Dimethyl Bromosuccinate is produced under strict quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC, NMR, and GC-MS, to verify identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess (ee), and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.