Description

n-(4-Methoxybenzyl)Glycine Methyl Ester Hcl is a high-purity, protected amino acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in the development of complex molecules, offering a reactive ester group and a protected amine for selective functionalization. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in peptide chemistry, medicinal chemistry, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediates: A key precursor in the multi-step synthesis of peptide-based drugs and other therapeutic compounds.
• Peptide Synthesis: Used as a protected glycine derivative in solid-phase and solution-phase peptide coupling reactions.
• Medicinal Chemistry Research: Employed in the design and construction of molecular libraries for drug discovery and lead optimization.
• Chemical Biology: Acts as a versatile scaffold for creating probes and tools to study biological systems and enzyme mechanisms.
• Agrochemical Synthesis: Can be utilized in the development of novel pesticides and herbicides requiring specific amino acid motifs.
• Academic & Industrial R&D: Serves as a fundamental reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Item	Details
Product Name	n-(4-Methoxybenzyl)Glycine Methyl Ester Hcl
CAS No.	20839-80-9
Molecular Formula	C11H15NO3 • HCl
Molecular Weight	245.70 g/mol
Synonyms	Glycine, N-[(4-methoxyphenyl)methyl]-, methyl ester, hydrochloride; Methyl N-(4-Methoxybenzyl)glycinate Hydrochloride; 4-Methoxybenzylglycine Methyl Ester Hydrochloride; PMB-Gly-OMe • HCl; N-(p-Methoxybenzyl)glycine methyl ester hydrochloride; Methyl 2-[(4-methoxybenzyl)amino]acetate hydrochloride; (4-Methoxybenzylamino)-acetic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our n-(4-Methoxybenzyl)Glycine Methyl Ester Hcl is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable, ensuring the material meets the rigorous standards required for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.