Description

2-O,3-O:4-O,5-o-Dibenzylidene-D-Arabinitol Acetate is a high-purity, protected carbohydrate derivative, specifically a benzylidene acetal of D-arabinitol acetate. This compound is a critical chiral intermediate and protecting group reagent in sophisticated organic synthesis, valued for its ability to impart stereochemical control. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and complex carbohydrate-based therapeutics. Its precise structure makes it indispensable for chemists requiring regioselective protection and manipulation of polyol frameworks.

Application

• Pharmaceutical Intermediate: Key chiral building block in the synthesis of nucleoside and nucleotide analogs for antiviral and anticancer research.
• Carbohydrate Chemistry: Used as a protected derivative of D-arabinitol for the regioselective synthesis of complex sugars and glycomimetics.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds.
• Protecting Group Reagent: The benzylidene groups provide orthogonal protection for diols in multi-step synthetic sequences.
• Biochemical Research: Utilized in studies exploring enzyme inhibitors and metabolic pathway modulators.
• Material Science: Potential monomer or precursor for chiral polymers and advanced materials with specific optical properties.

Basic Information

Product Name	2-O,3-O:4-O,5-o-Dibenzylidene-D-Arabinitol Acetate
CAS No.	20769-98-6
Molecular Formula	C21H22O7
Molecular Weight	386.40 g/mol
Synonyms	D-Arabinitol, 1-acetate, 2,3:4,5-bis-O-(phenylmethylene)-; 1-Acetyl-2,3:4,5-di-O-benzylidene-D-arabinitol; 2,3:4,5-Di-O-benzylidene-D-arabinitol 1-acetate; Di-O-benzylidene-D-arabinitol acetate; 1-O-Acetyl-2,3:4,5-di-O-benzylidene-D-arabinitol
EINECS	Contact for details

Quality Control

Every batch of 2-O,3-O:4-O,5-o-Dibenzylidene-D-Arabinitol Acetate is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for research and process development. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), chiral purity, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.