Description

1,2,3,4,5-Penta-o-Acetyl-B-D-Fructose is a fully acetylated derivative of fructose, serving as a crucial protected intermediate in synthetic organic chemistry. This compound is valued for its role in facilitating stereoselective glycosylation reactions and the synthesis of complex carbohydrate analogs. It is primarily needed by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical sectors for developing novel therapeutic agents and specialty sweeteners.

Application

• Pharmaceutical Intermediate: A key protected building block for the synthesis of nucleoside analogs, antiviral drugs, and other bioactive carbohydrate-based molecules.
• Glycosylation Reagent: Used in the stereoselective construction of glycosidic bonds for oligosaccharide and glycoconjugate synthesis.
• Carbohydrate Chemistry Research: An essential tool in academic and industrial R&D for studying fructose chemistry and developing new synthetic methodologies.
• Fine Chemical Production: Employed in the manufacture of specialty sweeteners, flavor precursors, and other high-value fructose derivatives.
• Bioconjugate Development: Useful for creating carbohydrate-protein or carbohydrate-drug conjugates for targeted delivery and diagnostic applications.

Basic Information

Product Name	1,2,3,4,5-Penta-o-Acetyl-B-D-Fructose
CAS No.	20764-61-8
Molecular Formula	C16H22O11
Molecular Weight	390.34 g/mol
Synonyms	Pentaacetyl-β-D-fructopyranose; β-D-Fructopyranose, 1,2,3,4,5-pentaacetate; 1,2,3,4,5-Penta-O-acetyl-β-D-fructopyranose; Penta-O-acetyl-β-D-fructose; Acetylated fructose; Fructose pentaacetate; β-D-Fructose pentaacetate; 20764-61-8
EINECS	Contact for details

Quality Control

Our 1,2,3,4,5-Penta-o-Acetyl-B-D-Fructose is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, optical rotation, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and production applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent hydrolysis of the acetyl groups.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	-80° to -90° (c=1 in CHCl₃)
Melting Point	95°C - 105°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.