Description

Methyl 3-Bromo-2-Methylpropanoate is a versatile brominated ester building block essential for advanced organic synthesis. Its reactive bromine and ester functionalities make it a critical intermediate for constructing complex molecular architectures. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to introduce key structural motifs and facilitate carbon-carbon bond formation.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring branched alkyl chains or halogenated segments.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the bromine atom acts as a reactive handle for further functionalization.
• Organic Synthesis Building Block: Employed in various coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to create complex organic molecules for material science and fine chemicals.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and polymerization processes.
• Polymer Modification: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Flavor and Fragrance Industry: Can be used as an intermediate for synthesizing specific ester compounds that contribute to complex aroma profiles.

Basic Information

Product Name	Methyl 3-Bromo-2-Methylpropanoate
CAS No.	20609-71-6
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	3-Bromo-2-methylpropanoic acid methyl ester; Methyl 3-bromo-2-methylpropionate; 2-Methyl-3-bromopropionic acid methyl ester; β-Bromoisobutyric acid methyl ester; Methyl β-bromoisobutyrate; 20609-71-6; NSC 3348
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-2-Methylpropanoate adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques like GC, HPLC, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to meet the rigorous demands of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.458 - 1.462
Density (20°C)	1.40 - 1.45 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.