Description

Benzene, 1-Isocyano-3-Methoxy- (9Ci) is a specialized aromatic isocyanate derivative, distinguished by the presence of a reactive isocyano group and a methoxy substituent. This compound serves as a versatile and high-value building block in advanced organic synthesis, enabling the construction of complex heterocyclic and functionalized molecular architectures. It is primarily required by pharmaceutical R&D, agrochemical innovators, and specialty chemical manufacturers for developing novel active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: Key synthon for the preparation of heterocyclic compounds, including potential drug candidates with benzoxazole or quinazoline cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized isocyanide-based ligands used in transition metal catalysis.
• Polymer Modification: Employed to introduce functional isocyanate groups into polymer backbones for cross-linking or property enhancement.
• Material Science Research: Utilized in the synthesis of advanced organic materials, such as organic semiconductors or metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a reactive handle for bioconjugation and the development of activity-based probes for protein labeling.

Basic Information

Product Name	Benzene, 1-Isocyano-3-Methoxy- (9Ci)
CAS No.	20600-55-9
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	3-Methoxyphenyl isocyanide; 1-Isocyano-3-methoxybenzene; m-Methoxyphenyl isocyanide; 3-Methoxybenzenisocyanid; Isocyanomethoxybenzene; 3-Methoxyphenyl isonitrile
EINECS	Contact for details

Quality Control

Our Benzene, 1-Isocyano-3-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its highly volatile and light-sensitive nature, prolonged exposure to air, moisture, or light should be avoided. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.