Description

7-Chloro-5-Ethoxy-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One is a high-purity benzodiazepine derivative, a key advanced pharmaceutical intermediate (API intermediate) valued for its precise chemical structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the central nervous system (CNS) sector. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a reference standard or starting material in drug discovery programs targeting neurological and psychiatric disorders.
• Process Development & Scale-Up: Employed in optimizing synthetic routes and manufacturing processes for pharmaceutical production.
• Analytical Standard: Utilized in quality control laboratories for method development, validation, and as a purity benchmark.
• Academic & Institutional Research: Supports chemical and pharmacological studies in university and institutional settings.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of specialized fine chemicals and APIs.

Basic Information

Product Name	7-Chloro-5-Ethoxy-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One
CAS No.	20430-79-9
Molecular Formula	C₁₂H₁₃ClN₂O₂
Molecular Weight	252.70 g/mol
Synonyms	7-Chloro-5-ethoxy-1-methyl-1,4-benzodiazepin-2(3H)-one; 5-Ethoxy-7-chloro-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Ethyl Loflazepate Impurity; Ethyl Loflazepate Related Compound; 1-Methyl-7-chloro-5-ethoxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 20430-79-9; Loflazepate Impurity
EINECS	Contact for details

Quality Control

Our 7-Chloro-5-Ethoxy-1-Methyl-1H-1,4-Benzodiazepin-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to GMP-grade standards and traceability ensures reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.