Description

Ethyl cis-2-(Dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate is a specialized chiral intermediate featuring a unique cyclohexene scaffold with both amino and ester functionalities. This compound matters for its role as a critical building block in the synthesis of complex pharmaceutical molecules, particularly those targeting neurological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel central nervous system (CNS) active drugs and other therapeutic agents.
• Asymmetric Synthesis: Utilized as a precursor or ligand in catalytic asymmetric reactions to construct stereochemically complex molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, complex organic compounds for various industrial applications.
• Academic Research: Used in universities and research institutes for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	Ethyl cis-2-(Dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
CAS No.	20380-56-7
Molecular Formula	C₁₇H₂₃NO₂
Molecular Weight	273.37 g/mol
Synonyms	Ethyl 2-(Dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylate; cis-2-(Dimethylamino)-1-phenyl-3-cyclohexenecarboxylic Acid Ethyl Ester; 1-Phenyl-2-(dimethylamino)-3-cyclohexenecarboxylic Acid Ethyl Ester; Ethyl 1-Phenyl-2-(dimethylamino)cyclohex-3-ene-1-carboxylate; cis-1-Phenyl-2-(dimethylamino)-3-cyclohexenecarboxylic Acid Ethyl Ester; 20380-56-7; Ethyl cis-2-(N,N-Dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl cis-2-(Dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.