Description

2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Azide is a key protected glycosyl donor and versatile synthetic intermediate in carbohydrate chemistry. This compound is essential for the efficient construction of complex oligosaccharides and glycoconjugates via click chemistry and other azide-based transformations. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for drug discovery, vaccine development, and the synthesis of novel bioactive molecules.

Application

• Glycosylation Reagent: A crucial building block for the stereoselective synthesis of 1,2-cis and 1,2-trans glycosidic linkages in oligosaccharide assembly.
• Click Chemistry Substrate: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to create triazole-linked glycoconjugates for drug discovery and bioconjugation.
• Pharmaceutical Intermediate: Serves as a precursor in the synthesis of nucleoside analogs, antiviral agents, and other glycosylated active pharmaceutical ingredients (APIs).
• Glycobiology Research: Enables the study of carbohydrate-protein interactions, cell surface labeling, and the development of diagnostic tools and probes.
• Material Science: Used to create functionalized polymers and surfaces with bioactive carbohydrate motifs.
• Agrochemical Synthesis: Intermediate in the development of novel glycosylated pesticides or plant growth regulators.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Azide
CAS No.	20369-61-3
Molecular Formula	C14H19N3O9
Molecular Weight	373.32 g/mol
Synonyms	2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl azide; 1-Azido-2,3,4,6-tetra-O-acetyl-α-D-glucopyranose; α-D-Glucopyranosyl azide, 2,3,4,6-tetraacetate; Tetra-O-acetyl-α-D-glucopyranosyl azide; Glucosyl azide tetraacetate; Azidotetraacetylglucose; α-Azidotetraacetylglucose; 1-Azido-1-deoxy-2,3,4,6-tetra-O-acetyl-α-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-α-D-Glucopyranosyl Azide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	+150° to +160° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.