Description

3-Nitro-L-Phenylalanine Methyl Ester Hcl is a chemically modified amino acid derivative, specifically the methyl ester hydrochloride salt of 3-nitro-L-phenylalanine. This compound serves as a crucial chiral building block and intermediate in advanced organic synthesis, offering precise stereochemical control. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, enzyme inhibitors, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in peptide-based drug discovery.
• Biochemical Research: Used in the study of enzyme-substrate interactions, as a precursor for enzyme inhibitors, and in proteomics research.
• Peptide Synthesis: An essential building block in solid-phase and solution-phase peptide synthesis (SPPS) for incorporating modified phenylalanine residues.
• Chemical Biology Probes: Serves as a starting material for synthesizing fluorescent or affinity tags to study biological processes.
• Agrochemical Research: Potential intermediate in the synthesis of novel, chiral agrochemicals and plant growth regulators.
• Academic & Industrial R&D: Employed in organic chemistry laboratories for methodological studies in asymmetric synthesis and catalysis.

Basic Information

Product Name	3-Nitro-L-Phenylalanine Methyl Ester Hcl
CAS No.	20299-36-9
Molecular Formula	C10H13N2O4 • HCl
Molecular Weight	260.68 g/mol (Free base: 224.22 g/mol)
Synonyms	L-Phenylalanine, 3-nitro-, methyl ester, hydrochloride; Methyl (2S)-2-amino-3-(3-nitrophenyl)propanoate hydrochloride; 3-Nitro-L-Phe-OMe • HCl; (S)-Methyl 2-amino-3-(3-nitrophenyl)propanoate hydrochloride; 3-Nitro-L-phenylalanine methyl ester hydrochloride; Methyl 3-nitro-L-phenylalaninate hydrochloride; NSC 334909; 3-Nitro-L-Phenylalanine Methyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Nitro-L-Phenylalanine Methyl Ester Hcl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.