Description

Diethoxyphosphinyl Isocyanate is a highly reactive organophosphorus compound that serves as a versatile building block for synthesizing complex molecules. Its value lies in its ability to introduce both the phosphoryl and isocyanate functional groups in a single step, enabling the creation of novel agrochemicals and pharmaceuticals. This product is essential for R&D chemists and process development scientists in the fine chemical, crop protection, and pharmaceutical intermediate sectors seeking to develop new active ingredients or functional materials.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of organophosphate insecticides, herbicides, and fungicides, where it is used to construct the active phosphoramidate or phosphoryl urea core.
• Pharmaceutical Synthesis: Employed in medicinal chemistry for the preparation of potential drug candidates, particularly those targeting enzymes where phosphorus-containing groups act as inhibitors or bioisosteres.
• Polymer Modification: Used to functionalize polymers and resins, imparting flame-retardant properties or creating reactive sites for further cross-linking via the isocyanate group.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel phosphorus-based ligands used in asymmetric catalysis and metal complexation.
• Chemical Research & Development: A valuable reagent for exploring new reaction pathways and creating libraries of compounds for high-throughput screening in various industrial research programs.

Basic Information

Product Name	Diethoxyphosphinyl Isocyanate
CAS No.	20039-33-2
Molecular Formula	C5H10NO4P
Molecular Weight	179.11 g/mol
Synonyms	Diethoxyphosphinyl isocyanate; Diethoxyphosphoroyl isocyanate; Isocyanic acid P,P-diethoxyphosphinyl ester; (Diethoxyphosphinyl)isocyanate; Phosphoroisocyanatidic acid diethyl ester; Diethyl phosphoroisocyanatidate; NSC 163081
EINECS	Contact for details

Quality Control

Every batch of Diethoxyphosphinyl Isocyanate is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as water, alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.18 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.