Description

(4-Chloro-Phenyl)-Propynoic Acid Ethyl Ester is a versatile organic building block characterized by its phenylacetylene and ester functionalities. This compound matters as a key synthetic intermediate, enabling the construction of more complex molecular architectures through reactions like Sonogashira coupling and cycloadditions. It is needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly those requiring a substituted phenylacetylene core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Organic Synthesis Building Block: Employed in Sonogashira coupling, Huisgen cycloaddition (click chemistry), and other catalytic cross-coupling reactions to form carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized for the preparation of specialized ligands for metal complexes used in homogeneous catalysis.
• Chemical Research & Development: A valuable tool in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	(4-Chloro-Phenyl)-Propynoic Acid Ethyl Ester
CAS No.	20026-96-4
Molecular Formula	C11H9ClO2
Molecular Weight	208.64 g/mol
Synonyms	Ethyl 3-(4-Chlorophenyl)propiolate; 4-Chlorophenylpropiolic Acid Ethyl Ester; Ethyl (4-Chlorophenyl)propiolate; 3-(4-Chlorophenyl)-2-propynoic Acid Ethyl Ester; Ethyl 4-Chlorophenylpropiolate; NSC 3349; Ethyl p-Chlorophenylpropiolate
EINECS	Contact for details

Quality Control

Our (4-Chloro-Phenyl)-Propynoic Acid Ethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed specifications from methods including HPLC, GC, and NMR are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.